Self-poisoning with Colchicum autumnale L. flowers

Citation
Vc. Danel et al., Self-poisoning with Colchicum autumnale L. flowers, J TOX-CLIN, 39(4), 2001, pp. 409-411
Citations number
12
Categorie Soggetti
Pharmacology,"Pharmacology & Toxicology
Journal title
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY
ISSN journal
07313810 → ACNP
Volume
39
Issue
4
Year of publication
2001
Pages
409 - 411
Database
ISI
SICI code
0731-3810(2001)39:4<409:SWCALF>2.0.ZU;2-5
Abstract
Report: A 44-year-old man ingested about 40 flowers of Colchicum autumnale L. The patient presented with nausea, vomiting, and abdominal pain 2 hours after ingestion and had diarrhea 14 hours after ingestion. Hematological va lues remained within normal range. Treatment was mainly supportive. The out come was favorable. The intoxication was confirmed by. high-performance liq uid chromatography-mass spectrometry. Maximal colchicine levels were 4.34 n g/mL at 13 hours in plasma and 5.43 ng/mL at 16 hours in erythrocytes. Conc lusion: We report one of the few symptomatic cases of Colchicum autumnale L . poisoning confirmed by toxicological analysis.