Regional complications after axillary lymphadenectomy are common and usuall
y involve perioperative skin dehiscence, wound infection, and seroma format
ion and later arm lymphedema. Gentle handling of tissues during operation,
and routine use of closed catheter suction drainage with direct external ax
illary compression with immobilization of the shoulder after nodal dissecti
on are advocated to minimize both the early and late sequelae. Healing by p
rimary intent is facilitated and the opportunity for reconnection of divide
d lymphatics (lymphangiogenesis and lymphvasculogenesis) are thereby optimi
zed.