Mixed echo train acquisition displacement encoding with stimulated echoes:An optimized DENSE method for in vivo functional imaging of the human heart

Mixed echo train acquisition displacement encoding with stimulated echoes ( meta-DENSE) is a phase-based displacement mapping technique suitable for im aging myocardial function. This method has been optimized for use with pati ents who have a history of myocardial infarction. The total scan time is 12 -14 heartbeats for an in-plane resolution of 2.8 x 2.8 mm(2). Myocardial st rain is mapped at this resolution with an accuracy of 2% strain in vivo. Co mpared to standard stimulated echo (STE) methods, both data acquisition spe ed and resolution are improved with inversion-recovery FID suppression and the meta-DENSE readout scheme. Data processing requires minimal user interv ention and provides a rapid quantitative feedback on the MRI scanner for ev aluating cardiac function. Published 2001 Wiley-Liss, Inc.(dagger)