Elaboration and formalization of current scientific knowledge of risks andpreventive measures illustrated by colorectal cancer

Objectives. Present the method used to elaborate and formalize current scie ntific knowledge to provide physicians with tools available on the Internet , that enable them to evaluate individual patient risk, give personalized p reventive recommendations or early screening measures. Methods. The approach suggested in this article is in line with medical pro cedures based on levels of evidence (Evidence-based Medicine). A cyclical p rocess for developing recommendations allows us to quickly incorporate curr ent scientific information. At each phase, the analysis is reevaluated by e xperts in the field collaborating on the project. The information is formal ized through the use of levels of evidence and grades of recommendations. G LIF model is used to implement recommendations for clinical practice guidel ines. Results: The most current scientific evidence incorporated in a cyclical pr ocess includes several steps: critical analysis according to the Evidence-b ased Medicine method; identification of predictive factors; setting-up of r isk levels; identification of prevention measures; elaboration of personali zed recommendation. The information technology implementation of the clinic al practice guideline enables physicians to quickly obtain personalized inf ormation for their patients. Cases of colorectal prevention illustrate our approach. Conclusions. Integration of current scientific knowledge is an important pr ocess. The delay between the, moment new information arrives and the moment the practitioner applies it, is thus reduced.