Convenient method for the preparation of 2 '-deoxyribosylurea by thymidineoxidation and NMR study of both anomers

Authors
Dubey, I Pratviel, G Robert, A Meunier, B
Citation
I. Dubey et al., Convenient method for the preparation of 2 '-deoxyribosylurea by thymidineoxidation and NMR study of both anomers, NUCLEOS NUC, 20(8), 2001, pp. 1463-1471
Citations number
21
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN journal
15257770 → ACNP
Volume
20
Issue
8
Year of publication
2001
Pages
1463 - 1471
Database
ISI
SICI code
1525-7770(2001)20:8<1463:CMFTPO>2.0.ZU;2-4
Abstract
The synthesis of 2 ' -deoxyribosylurea by thymidine oxidation with potassiu m permanganate followed, by alkaline hydrolysis of intermediates is describ ed. The anomeric configuration of the resulting products was studied by NMR spectroscopy.