2 '-O-modified oligoribonucleotides with terminal 3 '-3 '-internucleotide linkage and their derivatives

Authors
Novopashina, D Kuznetsova, M Venyaminova, A
Citation
D. Novopashina et al., 2 '-O-modified oligoribonucleotides with terminal 3 '-3 '-internucleotide linkage and their derivatives, NUCLEOS NUC, 20(4-7), 2001, pp. 903-907
Citations number
7
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN journal
15257770 → ACNP
Volume
20
Issue
4-7
Year of publication
2001
Pages
903 - 907
Database
ISI
SICI code
1525-7770(2001)20:4-7<903:2'OWT3>2.0.ZU;2-E
Abstract
A high RNA binding affinity and nuclease resistance of 2'-O-modified (2'-O- methyl, 2'-O-tetrahydropyranyl) oligoribonucleotides containing the "invert ed" T at the 3'-end have been shown. The synthesis and properties of new ph otoactivatable perfluoroarylazide derivatives of these oligoribonucleotides are discussed.