Citation
T. Sugiyama et al., Chemical cross-linking of peptides derived from RecA with single-stranded oligonucleotides containing 5-formyl-2 '-deoxyuridine, NUCLEOS NUC, 20(4-7), 2001, pp. 1079-1083
Citations number
10
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN journal
15257770
→ ACNP
Volume
20
Issue
4-7
Year of publication
2001
Pages
1079 - 1083
Database
ISI
SICI code
1525-7770(2001)20:4-7<1079:CCOPDF>2.0.ZU;2-Q
Abstract
We report the first example of chemical cross-linking of 5-formyl-2'-deoxyu
ridine containing oligonucleotides with oligopeptides through a Schiff base
formation. Twenty amino acid residue peptides investigated here were deriv
ed from the DNA binding site of RecA protein. We have demonstrated that the
lysine residue placed at the 6th or 8th position from the N-terminus of th
e peptide directly contacts with DNA.