A cyclobutane carbonucleoside with marked selectivity against TK+ and TK- varicella zoster virus

Authors
Lopez, C Balo, C Blanco, JM Fernandez, F De Clercq, E Balzarini, J
Citation
C. Lopez et al., A cyclobutane carbonucleoside with marked selectivity against TK+ and TK- varicella zoster virus, NUCLEOS NUC, 20(4-7), 2001, pp. 1133-1135
Citations number
3
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN journal
15257770 → ACNP
Volume
20
Issue
4-7
Year of publication
2001
Pages
1133 - 1135
Database
ISI
SICI code
1525-7770(2001)20:4-7<1133:ACCWMS>2.0.ZU;2-P
Abstract
Several cyclobutyladenine and analogous carbonucleosides were synthesized f rom 1R-alpha -pinene and their anti-viral activity was tested. One of them (3e) showed interesting selectivity against both TK+ and TK- VZV.