Synthesis of 2 ',3 '-dideoxy-2 ',3 '-didehydro nucleosides via a serendipitous route

Authors
Guo, Z Sanghvi, YS Brammer, LE Hudlicky, T
Citation
Z. Guo et al., Synthesis of 2 ',3 '-dideoxy-2 ',3 '-didehydro nucleosides via a serendipitous route, NUCLEOS NUC, 20(4-7), 2001, pp. 1263-1266
Citations number
6
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN journal
15257770 → ACNP
Volume
20
Issue
4-7
Year of publication
2001
Pages
1263 - 1266
Database
ISI
SICI code
1525-7770(2001)20:4-7<1263:SO2'''>2.0.ZU;2-P
Abstract
This paper describes a "green" synthesis of 2',3'-unsaturated 2',3'-dideoxy nucleosides via an electrochemical reaction. Using this approach d4T, d4U, ddA and ddI can be synthesized in high yields.