K. Deaterdeckard et al., DIMENSIONS AND DISORDERS OF ADOLESCENT ADJUSTMENT - A QUANTITATIVE GENETIC-ANALYSIS OF UNSELECTED SAMPLES AND SELECTED EXTREMES, Journal of child psychology and psychiatry and allied disciplines, 38(5), 1997, pp. 515-525
One of the fundamental questions for developmental psychopathology con
cerns the etiological links between the normal and abnormal. To what e
xtent do disorders differ quantitatively or qualitatively from variati
on in the normal range? Genetic research on the normal and the abnorma
l differs in terms of concepts, methods, statistics, and target audien
ces. An approach, referred to as ''DF'' analysis, provides a framework
for integrating these two worlds of genetic analysis. We applied trad
itional correlational analyses as well as DF (DeFries & Fulker, 1985)
analyses to mother and father ratings of adjustment of adolescent sibl
ings in a 3-year longitudinal twin and step-family study. At wave 1, t
he sample included 720 sibling pairs (average age of 12.9 years for th
e younger sibling and 14.5 years for the older siblings) and, in wave
2, 395 pairs still living at home. Both correlational analyses of the
entire sample and DF analyses of selected extremes suggested moderate
genetic influence and modest shared environmental influence for intern
alizing and externalizing behavior problems. Similar estimates were fo
und for unselected individual differences and selected extreme groups.
A framework is proposed that focuses on quantifying the etiologies of
disorders (QED) as measured on continuous dimensions.