Distinguishing Spitz tumors from malignant melanoma: Potential role of comparative genomic hybridization and fluorescence in situ hybridization in diagnosis and prognosis

Authors
Llewellyn, K Barnhill, RL
Citation
K. Llewellyn et Rl. Barnhill, Distinguishing Spitz tumors from malignant melanoma: Potential role of comparative genomic hybridization and fluorescence in situ hybridization in diagnosis and prognosis, ADV ANAT PA, 8(5), 2001, pp. 249
Citations number
8
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
ADVANCES IN ANATOMIC PATHOLOGY
ISSN journal
10724109 → ACNP
Volume
8
Issue
5
Year of publication
2001
Database
ISI
SICI code
1072-4109(200109)8:5<249:DSTFMM>2.0.ZU;2-T
Abstract
The distinction of Spitz tumors from melanoma is a major challenge to patho logists at least for a subset of cases. Herein the authors review a recent study utilizing the techniques of comparative genomic hybridization (CGH) a nd fluorescence in situ hybridization (FISH) to aid in the latter distincti on. The limitations of the study and two techniques as applied to solid tum ors are reviewed.