Choroidal neovascularization associated with aplasia of the optic nerve

PURPOSE: To report an unusual case of unilateral aplasia of the optic nerve associated with choroidal neovascularization. DESIGN: Observational case r eport. METHODS: In a 29-year-old female with optic nerve aplasia of the right eye and no choroidal neovascularization at age 23 years, choroidal neovasculari zation of the right eye was present by ophthalmoscopy and fluorescein angio graphy. RESULTS: Fluorescein angiography disclosed de novo choroidal neovasculariza tion corresponding to fibrovascular proliferation evident on ophthalmoscopy at age 29 years. CONCLUSION: Choroidal neovascularization may develop de novo during adult l ife in an eye with optic nerve aplasia. (Am J Ophthalmol 2001;132:439-440. (C) 2001 by Elsevier Science Inc. All rights reserved.).