Bidentate carbenoid ester coordination in ruthenium(II) Schiff-base complexes leading to excellent levels of diastereo- and enantioselectivity in catalytic alkene cyclopropanation

Authors
Munslow, IJ Gillespie, KM Deeth, RJ Scott, P
Citation
Ij. Munslow et al., Bidentate carbenoid ester coordination in ruthenium(II) Schiff-base complexes leading to excellent levels of diastereo- and enantioselectivity in catalytic alkene cyclopropanation, CHEM COMMUN, (17), 2001, pp. 1638-1639
Citations number
24
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
17
Year of publication
2001
Pages
1638 - 1639
Database
ISI
SICI code
1359-7345(20010907):17<1638:BCECIR>2.0.ZU;2-G
Abstract
Exceptionally high stereoselectivity (ee less than or equal to 98%, dr less than or equal to 99:1) in the cyclopropanation of alkenes with ethyl diazo acetate using a non-planar ruthenium(II) Schiff-base precatalyst is a resul t of eta C-2,O binding of the carbenoid ester intermediate, according to DF T calculations.