Powerful Claisen condensation and Claisen-aldol tandem reaction of alpha,alpha-dialkylated esters promoted by ZrCl4-(Pr2NEt)-Pr-i

Authors
Tanabe, Y Hamasaki, R Funakoshi, S
Citation
Y. Tanabe et al., Powerful Claisen condensation and Claisen-aldol tandem reaction of alpha,alpha-dialkylated esters promoted by ZrCl4-(Pr2NEt)-Pr-i, CHEM COMMUN, (17), 2001, pp. 1674-1675
Citations number
12
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
17
Year of publication
2001
Pages
1674 - 1675
Database
ISI
SICI code
1359-7345(20010907):17<1674:PCCACT>2.0.ZU;2-2
Abstract
Powerful Claisen ester condensations of alpha,alpha -dialkylated esters med iated by ZrCl4-(Pr2NEt)-Pr-i were performed to give the corresponding therm odynamically unfavorable alpha,alpha -dialkylated beta -ketoesters, and Cla isen-aldol tandem reactions between an intermediary Zr-enolate of a a,a-dia lkylated beta -ketoester and aldehydes also proceeded.