Paxillin-ARF GAP signaling and the cytoskeleton

Authors
Turner, CE West, KA Brown, MC
Citation
Ce. Turner et al., Paxillin-ARF GAP signaling and the cytoskeleton, CURR OP CEL, 13(5), 2001, pp. 593-599
Citations number
55
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN CELL BIOLOGY
ISSN journal
09550674 → ACNP
Volume
13
Issue
5
Year of publication
2001
Pages
593 - 599
Database
ISI
SICI code
0955-0674(200110)13:5<593:PGSATC>2.0.ZU;2-Z
Abstract
Several new families of ARF GTPase activating proteins (ARF GAPs) have been described recently that associate with paxillin and other cytoskeletal and signaling proteins. Important insights have been gained regarding their su bcellular distribution, enzymatic specificity and protein scaffold function . Evidence suggests an important role for ARF GAPs in mediating changes in the cell's actin cytoskeleton in response to adhesion and growth factor sti mulation.