Some cases of Menetrier's disease associated with Helicobacter pylori (HP)
have recently been reported in the literature. We report here the case of a
51-year-old man with a diagnosis of Menetrier's disease who had previously
been unsuccessfully treated with H-2 antagonists. A subsequent demonstrati
on of HP infection led us to treat the patient with an eradicating therapy
which prompted complete regression of clinical symptoms, resolution of the
gastric endoscopic picture, and absence of HP on gastric histology. This re
sult, in accordance with others in the literature, indicates an eventual as
sociation of HP infection with Menetrier's disease and that consequent ther
apy is mandatory. Copyright (C) 2001 S. Karger AG, Basel.