Resolution of Menetrier's disease after Helicobacter pylori eradicating therapy

Some cases of Menetrier's disease associated with Helicobacter pylori (HP) have recently been reported in the literature. We report here the case of a 51-year-old man with a diagnosis of Menetrier's disease who had previously been unsuccessfully treated with H-2 antagonists. A subsequent demonstrati on of HP infection led us to treat the patient with an eradicating therapy which prompted complete regression of clinical symptoms, resolution of the gastric endoscopic picture, and absence of HP on gastric histology. This re sult, in accordance with others in the literature, indicates an eventual as sociation of HP infection with Menetrier's disease and that consequent ther apy is mandatory. Copyright (C) 2001 S. Karger AG, Basel.