Sexual function can be altered in patients by many neurological disorders a
ffecting the cerebrum, the brain stem, the spinal cord, the spinal roots or
the peripheral nerves. It can also be prominently affected in patients wit
h an underlying undiagnosed neurological disease. Traditionally, practising
neurologists have not paid much attention to sexual dysfunction in their p
atients, partly because therapeutic possibilities were scant. Sexual dysfun
ction, however, is observed in many neurological disorders, and may arise a
s a primary neurogenic disorder. Although not as obviously limiting as, for
instance, paresis and pain, it is most disruptive for patients' lives. Wit
h emerging awareness of the primary importance of quality of life as the mo
st important indicator of good patient management. and with the advent of m
ore effective treatment of sexual dysfunction, it is no longer acceptable t
o ignore this very important dimension of life.
In this review we will present the anatomical and physiological basis of th
e sexual response, the clinical approach to patients with sexual dysfunctio
n, the characteristics of symptoms in neurological disorders, how to take a
case history, diagnostic procedures and the treatment possibilities.