Inhibition of HIV integrase by 4-hydroxycoumarin dimer. Bearing aniline mustard moiety

Authors
Mao, PCM Mouscadet, JF Leh, H Auclair, C Hsu, LY
Citation
Pcm. Mao et al., Inhibition of HIV integrase by 4-hydroxycoumarin dimer. Bearing aniline mustard moiety, HETEROCYCLE, 55(7), 2001, pp. 1263
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
55
Issue
7
Year of publication
2001
Database
ISI
SICI code
0385-5414(20010701)55:7<1263:IOHIB4>2.0.ZU;2-V
Abstract
The design, synthesis of novel HIV-integrase (HIV-IN) inhibitors possessing the 4-hydroxycoumarin dimer bearing aniline mustard moiety are described. These compounds showed good inhibitory activity against HIV-IN.