Small bowel necrosis is known as a rare, but serious complication of jejuna
l tube feeding. We report a case of non-occlusive small bowel necrosis with
gastric tube feeding. The patient had a moderate multiple trauma with head
injury. Abdominal distension developed after several days of uneventful na
sogastric tube feeding. At laparotomy patchy necrosis of the small bowel wa
s found without signs of bowel obstruction or impaired mesenteric perfusion
. The patient recovered after a prolonged ICU stay. In this case the large
doses of clonidine, given due to an alcohol withdrawal syndrome, were suspe
cted to be a major contributing factor to the development of the small bowe
l necrosis by impairing gut motility and mucosal perfusion. We conclude tha
t, first, small bowel necrosis can occur after primarily uneventful enteral
feeding, even with gastric feeding; second, clonidine can dramatically imp
air gastrointestinal function in critically ill patients by impairing gut m
otility and mucosal perfusion.