The polyphenol derivatives possess many biological and pharmacological
properties. However, the main therapeutical uses are limited to hepat
oprotective and vasculoprotective activities of flavonoids (sensu larg
o). This review will summarize some of the important and recently upda
ted reports of in vitro and in vivo biological assays to show antioxid
ative, antihypertensive, antiphlogistic, antiviral, potent antitumoral
and chimiopreventive activities.