Heteroresistance to vancomycin in Enterococcus faecium

Authors
Alam, MR Donabedian, S Brown, W Gordon, J Chow, JW Zervos, MJ Hershberger, E
Citation
Mr. Alam et al., Heteroresistance to vancomycin in Enterococcus faecium, J CLIN MICR, 39(9), 2001, pp. 3379-3381
Citations number
12
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
39
Issue
9
Year of publication
2001
Pages
3379 - 3381
Database
ISI
SICI code
0095-1137(200109)39:9<3379:HTVIEF>2.0.ZU;2-A
Abstract
This study presents the first report of vancomycin heteroresistance in an E nterococcus faecium isolate from a patient. The original isolate was suscep tible in vitro to vancomycin. E-tests showed growth of subcolonies in a zon e of inhibition with a vancomycin MIC of >256 mug/ml. Both the susceptible and resistant colonies were from the same strain as determined by PFGE, and both contained the vanA gene as determined by PCR.