Mag. Delvado et al., SCHIFF-BASES OF POLY-L-LYSINE AND SOME COMPOUNDS OF THE VITAMIN-B-6 GROUP - INFLUENCE OF POLYPEPTIDIC STRUCTURE, Journal of molecular catalysis. A, Chemical, 123(1), 1997, pp. 9-13
The apparent rate constants of formation (k(1)) and hydrolysis (k(2))
of the Schiff bases formed between pyridoxal and poly-L-lysine has bee
n fitted to a kinetic scheme that involves the different protonated sp
ecies in the reaction medium and the individual rate constants of form
ation (k(1)(i)) and hydrolysis (k(2)(i)). A Bronsted plot with alpha =
0.67 is in accord with an acid catalytic intramolecular process. The
effects of hydrophobic medium due to the presence of the macromolecule
on the formation and hydrolysis of Schiff bases from FL, DPL and PLP
with poly-L-lysine is discussed.