SCHIFF-BASES OF POLY-L-LYSINE AND SOME COMPOUNDS OF THE VITAMIN-B-6 GROUP - INFLUENCE OF POLYPEPTIDIC STRUCTURE

Authors
DELVADO MAG GOROSTIDI GRE BLANCO JGS BLANCO FG
Citation
Mag. Delvado et al., SCHIFF-BASES OF POLY-L-LYSINE AND SOME COMPOUNDS OF THE VITAMIN-B-6 GROUP - INFLUENCE OF POLYPEPTIDIC STRUCTURE, Journal of molecular catalysis. A, Chemical, 123(1), 1997, pp. 9-13
Citations number
25
Categorie Soggetti
Chemistry Physical
Journal title
Journal of molecular catalysis. A, Chemical → ACNP
ISSN journal
13811169
Volume
123
Issue
1
Year of publication
1997
Pages
9 - 13
Database
ISI
SICI code
1381-1169(1997)123:1<9:SOPASC>2.0.ZU;2-A
Abstract
The apparent rate constants of formation (k(1)) and hydrolysis (k(2)) of the Schiff bases formed between pyridoxal and poly-L-lysine has bee n fitted to a kinetic scheme that involves the different protonated sp ecies in the reaction medium and the individual rate constants of form ation (k(1)(i)) and hydrolysis (k(2)(i)). A Bronsted plot with alpha = 0.67 is in accord with an acid catalytic intramolecular process. The effects of hydrophobic medium due to the presence of the macromolecule on the formation and hydrolysis of Schiff bases from FL, DPL and PLP with poly-L-lysine is discussed.