There is a clear need for standardized measures to assess health status tha
t are valid and appropriate to the needs of children with orthopaedic probl
ems. The Child Health Questionnaire and the American Academy of Orthopaedic
Surgeons Pediatric Outcomes Data Collection Instrument, two new pediatric
health status measures, were assessed for their ability to detect differenc
es in health states in a pediatric orthopaedic population. The instruments
have a range of scales designed to measure various aspects of physical and
psychosocial health. Two hundred forty-two patients with wide-ranging diagn
oses were enrolled in this cross-sectional study. The instruments exhibited
ceiling effects in some domains but generally performed as they were inten
ded in this large cohort. Using secondary factor analysis, it was shown tha
t the domains of the instruments appropriately distinguish physical and psy
chosocial health. Several domains from each instrument discriminated betwee
n diagnosis groups and patients with varying numbers of comorbidities. Both
of these measures show significant promise and have an important role in h
elping define the outcomes of children with orthopaedic problems.