Surfactant lavage and replacement in meconium aspiration syndrome with pulmonary hemorrhage

We reported two case studies of meconium aspiration syndrome (MAS) with pul monary hemorrhage in which we applied surfactant lavage and replacement. Su rfactant lavage and replacement of MAS with pulmonary hemorrhage appears to be effective and safe adjunctive therapy. The relatively small replacement doses of surfactant required may be attributed to surfactant lavage follow ed by surfactant replacement. We suggest that surfactant lavage and replace ment of MAS with pulmonary hemorrhage should be further investigated by a r andomized controlled trial.