Background. Information about spontaneous remission of chronic urticaria is
limited.
Objective: To investigate the natural course of urticaria, we followed up 2
20 adults in a prospective study.
Methods: Patients were followed up for I to 3 years to evaluate interventio
ns, to detect latent causes, and to study the natural course of urticaria.
The diagnosis was made by detailed history-taking as well as laboratory and
provocation tests.
Results: Thirty-five percent of all patients were free of symptoms after I
year. In 28.9% of patients, symptoms had decreased. Spontaneous remission o
ccurred in 47.4% of the patients in whom no cause of their urticaria and/or
angioedema could be identified and in only 16.4% of the patients with phys
ical urticaria. A cause could be identified in 53.1% of the patients, Thirt
y-six percent of the patients had idiopathic urticaria. Chronic idiopathic
urticaria combined with physical urticaria occurred in 10.9%.
Conclusion: In general the prognosis for spontaneous remission is reasonabl
e, with the exception of the subgroup (33.2%) with physical urticaria.