A concise and efficient stereoselective synthesis of protected (2R,1 ' S,2' S)-2-(carboxycyclopropyl)glycine (D-CCG-I)

Authors
Mohapatra, DK
Citation
Dk. Mohapatra, A concise and efficient stereoselective synthesis of protected (2R,1 ' S,2' S)-2-(carboxycyclopropyl)glycine (D-CCG-I), J CHEM S P1, (16), 2001, pp. 1851-1852
Citations number
24
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 → ACNP
Issue
16
Year of publication
2001
Pages
1851 - 1852
Database
ISI
SICI code
1472-7781(20010821):16<1851:ACAESS>2.0.ZU;2-R
Abstract
The stereoselective synthesis of protected D-carboxycyclopropylglycine (D-C CG-I) was achieved as an extension of Taguchi's protocol for Simmons-Smith cyclopropanation to a chiral, amino-containing allyl alcohol derivative, in 8 steps (40% overall yield).