Evaluation of combining kava extract with hormone replacement therapy in the treatment of postmenopausal anxiety

Objective: to evaluate the efficacy of combining kava extract with hormone replacement therapy in the treatment of menopausal anxiety. Materials and m ethods: HAMA score was evaluated before and after therapy in four groups of women in menopause (duration of menopause ranged from I to 12 years). The groups were treated with hormone replacement therapy (with and without prog estogens) and kava extract or placebo for 6 months. Results: A significant reduction in HAMA score was observed in all four groups of women. The reduc tion was more significant in groups taking kava extract than in groups on h ormones only. Discussion: The combined use of hormone replacement therapy a nd kava extract seems to be effective against menopausal anxiety. Kava extr act accelerates resolution of psychological symptoms while hormone therapy safeguards against osteoporosis and cardiovascular disease. (C) 2001 Elsevi er Science Ireland Ltd. All rights reserved.