Tracheoesophageal voice prostheses in laryngectomized patients commonly det
eriorate due to the presence of yeasts, particularly Candida species. We de
scribe the first case of colonization of such a device by Cryptococcus neof
ormans in a patient with a history of glottic carcinoma. The isolate showed
an identical genomic pattern with C. neoformans from pigeon excreta in the
patient's environment.