Herpesvirus DNA in peripheral blood mononuclear cells of some patients with Meniere's disease

Authors
Takahashi, K Aono, T Shichinohe, M Tamura, M Iwata, Y Yamanishi, K Shigeta, S
Citation
K. Takahashi et al., Herpesvirus DNA in peripheral blood mononuclear cells of some patients with Meniere's disease, MICROB IMMU, 45(9), 2001, pp. 635-638
Citations number
21
Categorie Soggetti
Microbiology
Journal title
MICROBIOLOGY AND IMMUNOLOGY
ISSN journal
03855600 → ACNP
Volume
45
Issue
9
Year of publication
2001
Pages
635 - 638
Database
ISI
SICI code
0385-5600(2001)45:9<635:HDIPBM>2.0.ZU;2-V
Abstract
Herpes simplex virus-1 (HSV) or varicella zoster virus (VZV) DNA was detect ed by nested polymerase chain reaction in peripheral blood mononuclear cell s of patients with Meniere's disease (one of 28 patients for HSV-1, 2 of 28 patients for VZV) during acute illness (within 5 days after onset). On the other hand, neither HSV-1 DNA or VZV DNA was detected in PBMCs of 50 age- and sex-matched healthy individuals and 50 pregnant women. These findings m ay imply that reactivation of HSV-1 or VZV may be associated with the devel opment of some cases of Meniere's disease.