In fish, flow of respiratory medium is large, and oxygen utilization in the
respiratory organ is high. The regular decrease in the mass-specific rate
of metabolism with increasing body mass is qualitatively and quantitatively
explained principally by a combination of an increase in the relative size
of tissues of low metabolic activity and a decrease in the rate of tissue
respiration with increasing body mass. Mass-specific metabolism is lower in
a grouped fish than in a solitary one in group-living fishes, and vice ver
sa in solitary-living fishes. The snakehead takes O-2, mainly from air and
eliminates CO2 almost exclusively to water. The fish morphologically and ph
ysiologically shows a double circulation composed of respiratory circulatio
n and systemic circulation. Large carangid fishes show myomere subsegmentat
ion and double-tracking of the segmental vessels. These modifications are c
onsidered to overcome the restriction imposed by a small number of myomeres
in developing a large body and an active swimming ability. Erythrocytes ar
e supplied from the spleen into the circulating blood during swimming and i
n hypoxic water. Fish spleen has microcirculatory pathways which are consid
ered to function for rapid drainage of erythrocytes.