The 5,6-and 4,5-benzo derivatives of 1-hydroxy-7-azabenzotriazole

Authors
Carpino, LA Ferrer, FJ
Citation
La. Carpino et Fj. Ferrer, The 5,6-and 4,5-benzo derivatives of 1-hydroxy-7-azabenzotriazole, ORG LETT, 3(18), 2001, pp. 2793-2795
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
18
Year of publication
2001
Pages
2793 - 2795
Database
ISI
SICI code
1523-7060(20010906)3:18<2793:T54DO1>2.0.ZU;2-D
Abstract
Syntheses of the two benzo derivatives of HOAt are described. Conversion of the two isomers to the corresponding onium-style coupling reagents gave in one case a guandinium species 14 and in the other, presumably as a result of steric factors, a uronium species 15. The two systems are compared as to their effectiveness in peptide coupling processes.