Mp. Lopez-deber et al., Synthesis of N-(3-arylpropyl)amino acid derivatives by sonogashira types of reaction in aqueous media, ORG LETT, 3(18), 2001, pp. 2823-2826
N-Propargylamino acids and peptides. including them can be efficiently deri
vatized in aqueous media with a wide variety of (hetero)aryl halides by cro
ss-coupling reactions catalyzed by palladium on carbon (10% Pd/C).