Toxicity of over-the-counter cough and cold medications

Citation
Vl. Gunn et al., Toxicity of over-the-counter cough and cold medications, PEDIATRICS, 108(3), 2001, pp. NIL_111-NIL_115
Citations number
34
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
PEDIATRICS
ISSN journal
00314005 → ACNP
Volume
108
Issue
3
Year of publication
2001
Pages
NIL_111 - NIL_115
Database
ISI
SICI code
0031-4005(200109)108:3<NIL_111:TOOCAC>2.0.ZU;2-X
Abstract
Over-the-counter (OTC) cough and cold medications are marketed widely for r elief of common cold symptoms, and yet studies have failed to demonstrate a benefit of these medications for young children. In addition, OTC medicati ons can be associated with significant morbidity and even mortality in both acute overdoses and when administered in correct doses for chronic periods of time. Physicians often do not inquire about OTC medication use, and par ents (or other caregivers) often do not perceive OTCs as medications. We pr esent 3 cases of adverse outcomes over a 13-month period-including 1 death- as a result of OTC cough and cold medication use. We explore the toxicities of OTC cough and cold medications, discuss mechanisms of dosing errors, an d suggest why physicians should be more vigilant in specifically inquiring about OTCs when evaluating an ill child.