Failed challenge with quetiapine after neuroleptic malignant syndrome withconventional antipsychotics

Authors
Hatch, CD Lund, BC Perry, PJ
Citation
Cd. Hatch et al., Failed challenge with quetiapine after neuroleptic malignant syndrome withconventional antipsychotics, PHARMACOTHE, 21(8), 2001, pp. 1003-1006
Citations number
24
Categorie Soggetti
Pharmacology
Journal title
PHARMACOTHERAPY
ISSN journal
02770008 → ACNP
Volume
21
Issue
8
Year of publication
2001
Pages
1003 - 1006
Database
ISI
SICI code
0277-0008(200108)21:8<1003:FCWQAN>2.0.ZU;2-F
Abstract
Neuroleptic malignant syndrome (NMS) is an uncommon but potentially life-th reatening adverse effect associated with conventional antipsychotic agents. The syndrome is characterized by muscular rigidity, hyperpyrexia, altered consciousness, and autonomic dysfunction. Few cases of quetiapine-induced N MS have been reported. A 54-year-old man was unsuccessfully challenged with quetiapine after conventional antipsychotic-induced NMS.