The synthesis of novel substituted 2,5-dioxo-1,2,3,4,5,6,7,8-octahydroquinolines without solvent under microwave irradiation

Authors
Tu, SJ Wei, QH Ma, HJ Shi, DQ Gao, Y Cui, GY
Citation
Sj. Tu et al., The synthesis of novel substituted 2,5-dioxo-1,2,3,4,5,6,7,8-octahydroquinolines without solvent under microwave irradiation, SYN COMMUN, 31(17), 2001, pp. 2657-2661
Citations number
8
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
17
Year of publication
2001
Pages
2657 - 2661
Database
ISI
SICI code
0039-7911(2001)31:17<2657:TSONS2>2.0.ZU;2-L
Abstract
A convenient synthetic method for substituted 2,5-dioxo-1,2,3,4,5,6,7,8-oct ahydroquinolines is described. Heating Meldrum's acid, dimedone, ammonium a cetate and different aromatic aldehydes without a solvent in a microwave ir radiation for 2-5 minutes affords 4 in 72-86% yield. The structure of these compounds has been thoroughly studied by x-ray crystallographic analysis.