Total synthesis of (+/-)-fusaricide

Authors
Snider, BB Smith, RB
Citation
Bb. Snider et Rb. Smith, Total synthesis of (+/-)-fusaricide, SYN COMMUN, 31(17), 2001, pp. 2667-2679
Citations number
24
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
17
Year of publication
2001
Pages
2667 - 2679
Database
ISI
SICI code
0039-7911(2001)31:17<2667:TSO(>2.0.ZU;2-D
Abstract
Condensation of pyridone 6 with enal 25 using DMAP in EtOH at 150 degreesC afforded 8% of the desired Diels-Alder adduct 22, 8% of the bridged adduct 36 and 1-2% of a partially pure cis-fused adduct 37 of unknown stereochemis try. Hydroxylation of 22 completed a short synthesis of fusaricide (1).