Mechanisms of chemical carcinogenesis and application to human cancer riskassessment

Authors
Williams, GM
Citation
Gm. Williams, Mechanisms of chemical carcinogenesis and application to human cancer riskassessment, TOXICOLOGY, 166(1-2), 2001, pp. 3-10
Citations number
54
Categorie Soggetti
Pharmacology & Toxicology
Journal title
TOXICOLOGY
ISSN journal
0300483X → ACNP
Volume
166
Issue
1-2
Year of publication
2001
Pages
3 - 10
Database
ISI
SICI code
0300-483X(20010914)166:1-2<3:MOCCAA>2.0.ZU;2-Y
Abstract
The distinction between DNA-reactive and epigenetic carcinogens and their r oles in oncogenesis is reviewed. An approach to cancer hazard assessment ba sed upon mechanisms is described. (C) 2001 Elsevier Science Ireland Ltd. Al l rights reserved.