The author discusses the reviewer's task of making the overall judgment abo
ut the suitability of the manuscript based on their evaluations using the r
eview criteria. No one formula for developing an overall judgment exists an
d, in the absence of a fatal flaw, arriving at a judgment means each review
er must weigh the study's performance based on the wide range of review cri
teria. In the end, the reviewer is expected to provide a clear, consistent,
and useful recommendation to the editor, and a constructive reply to the a
uthor.