Meningeal inflammatory pseudotumour: A case report

We report the case of a meningeal inflammatory pseudotumour occurring in a 23-year-old male presenting with focal seizures and headaches. Brain imagin g techniques showed a 3.5 cm left parietal meningeal tumour. Histology of t he surgical specimen showed a dense lymphoid infiltrate permeating the dura mater and leptomeninges, consisting of a predominant polyclonal B cell pop ulation as confirmed by immunophenotyping and genotyping. Cultures of serum , CSF, and surgical specimen were negative and there was no serological evi dence of a systemic dysimmune disease. The postoperative course was complic ated by an episode of brain oedema resolving under steroid therapy. The pat ient, free from all medication, is asymptomatic at 3 years of follow-up. We discuss previously published cases and the nosology of intracranial inflam matory pseudotumours.