A 48-year-old man with no significant medical history presented to the emer
gency department of a large, urban, tertiary-care hospital complaining of d
ouble vision and unsteady gait. Physical examination was remarkable for an
isolated, unilateral sixth nerve palsy. After comprehensive testing, a fina
l diagnosis of myasthenia gravis was made. The patient's unsteady gait was
a manifestation of sensory distortion from the diplopia and corrected when
the patient closed his eyes. The presentation of myasthenia gravis as an is
olated sixth nerve palsy is unprecedented in the emergency medicine literat
ure. (Am J Emerg Med 2001;19:410-412. Copyright (C) 2001 by W.B. Saunders C
ompany).