Ts. Ahuja et al., Late recurrence of lupus nephritis in a renal transplant recipient: Response to mycophenolate mofetil, AM J MED SC, 322(3), 2001, pp. 166-169
Citations number
22
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Clinically significant recurrence of lupus nephritis in the renal allograft
is low, with an incidence of 1 to 3%, and usually occurs within the first
6 years after transplantation. We report an unusual case of a patient with
end-stage renal disease caused by lupus nephritis who received a kidney tra
nsplant from a living relative; 13 years later, the patient had a severe re
currence of diffuse proliferative lupus nephritis. The patient relapsed aft
er receiving intravenous cyclophosphamide therapy and had a partial respons
e to oral mycophenolate mofetil. In this report we review the risk factors
for the recurrence of the systemic lupus erythematosus in the kidney graft
and the anti-lupus activity of mycophenolate mofetil.