Patch angioplasty during carotid endarterectomy (CEA) has been shown to red
uce the incidence of both early and late complications. Controversy continu
es, however, over the ideal patch material. Bovine pericardium (Vascu-Guard
Biovascular Inc., Saint Paul, MN) offers an attractive alternative to othe
r patch materials because of its handling and suturing characteristics that
are similar to that of autogenous material. This study examines the periop
erative and midterm results of bovine pericardial patch angioplasty during
CEA. We studied 112 patients who underwent 129 CEAs with bovine pericardial
patch angioplasty during an 18-month period. Data were collected regarding
demographics, operative indications, perioperative complications, and the
occurrence of late adverse outcomes based primarily on follow-up arterial d
uplex studies. Among this group there were 63 male (56%) and 49 female (44%
) patients whose mean age was 71.8 +/-9.1 years. In these patients there wa
s the typical distribution of atherosclerotic risk factors. Seventy-four pa
tients (66%) had symptomatic disease preoperatively and the remaining 38 pa
tients (34%) were asymptomatic. Temporary cranial nerve palsy occurred in t
hree patients (2%). There were no perioperative strokes, acute occlusions,
bleeding episodes requiring reoperation, or deaths. The patients were follo
wed up to 54 months postoperatively with a mean follow-up time of 41.7 +/-4
.4 months. During this period two patients (2%) developed three significant
restenoses (70-99%). All required reoperation. There were no asymptomatic
occlusions, infections, aneurysms, or rupture. These data demonstrate that
bovine pericardial patch angioplasty during CEA is associated with a low in
cidence of both perioperative and midterm adverse outcomes.