The vast evolutionary gulf between plants and animals-in terms of structure
, composition, and many environmental factors-would seem to preclude the po
ssibility that these organisms could act as receptive hosts to the same mic
roorganism. However, some pathogens are capable of establishing themselves
and thriving in members of both the plant and animal kingdoms. The identifi
cation of functionally conserved virulence mechanisms required to infect ho
sts of divergent evolutionary origins demonstrates the remarkable conservat
ion in some of the underlying virulence mechanisms of pathogenesis and is c
hanging researchers' thinking about the evolution of microbial pathogenesis
.