In the Netherlands, a syndrome affecting several species of older Amazon pa
rrots (Amazona sp.) has been described. This syndrome was characterized as
a chronic respiratory disease resulting in exercise intolerance. Pathologic
al examination revealed loss of functional lung tissue, pulmonary interstit
ial fibrosis, and right heart failure. Haematology revealed an elevated pac
ked cell volume as a result of an increase in erythrocyte size and an incre
ased haemoglobin mass per erythrocyte. In two patients, hypoxia and hyperca
pnia were demonstrated. The aetiology of this syndrome is currently not kno
wn. The microscopic lesions resemble those found in Diffuse Interstitial Fi
brosis in humans.