Lactosylurea dihydrate -galactopyranosyl-1-N-beta-D-glucopyranosyl)ure
a], C13H24N2O11.2H(2)O, crystallizes as a dihydrate in the space group
P1. There are twelve distinct hydrogen bonds, including one intramole
cular hydrogen bond joining the glucose and galactose rings. This stru
cture determination establishes that the reaction of urea with lactose
does not lead to rearrangement or to an acyclic form of lactose and t
hat the urea forms a beta-N-glycoside linkage.