Pulmonary small lymphocytic lymphoma (mucosa-associated lymphoid tissue type) associated with pulmonary hyalinizing granuloma

A case of pulmonary hyalinizing granuloma (PHG) and concomitant low-grade, small lymphocytic lymphoma of the lung is presented. This is the first occu rrence of pulmonary lymphoma in patients with PHG ever reported. The infilt rates around a left lower lobe nodule with left pleural effusion and thicke ning seen on chest CT were histologically proven to be lymphomatous infiltr ates of the lung, pleura, and chest wall muscle. We believe that the lympho ma developed around the nodule and spread to the pleura and muscle in our p atient. When infiltrates around the nodules, pleural effusion, or adenopath y are developed in a patient with proven PHG, close follow-up, biopsy, or c areful cytology should be seriously considered to rule out a developing lym phoma.