Excretory-secretory antigens of Trypanosoma cruzi are potentially useful for serodiagnosis of chronic Chagas' disease

Authors
Nakazawa, M Rosa, DS Pereira, VRA Moura, MO Furtado, VC Souza, WV Barros, MDDS Abath, FGC Gomes, YM
Citation
M. Nakazawa et al., Excretory-secretory antigens of Trypanosoma cruzi are potentially useful for serodiagnosis of chronic Chagas' disease, CL DIAG LAB, 8(5), 2001, pp. 1024-1027
Citations number
24
Categorie Soggetti
Immunology
Journal title
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
ISSN journal
1071412X → ACNP
Volume
8
Issue
5
Year of publication
2001
Pages
1024 - 1027
Database
ISI
SICI code
1071-412X(200109)8:5<1024:EAOTCA>2.0.ZU;2-D
Abstract
The reactivities of sera from chronic chagasic patients against the trypoma stigote excreted-secreted antigens (TESA) of Trypanosoma cruzi strains with different biodemes were analyzed by TESA-blot and TESA-enzyme-linked immun osorbent assay (ELISA). Although both tests presented high sensitivity and specificity, TESA-ELISA is more appropriate for screening a larger number o f samples.