A COMPARISON OF SUSCEPTIBILITY RESULTS OF THE BACTEROIDES-FRAGILIS GROUP AND OTHER ANAEROBES BY TRADITIONAL MIC RESULTS AND STATISTICAL-METHODS

Antimicrobial susceptibility is compared by MIC values reflecting acti vity by weight and/or percentage of strains resistant. This study esta blishes these parameters in vitro in the traditional fashion and exten ds analysis statistically for various groups of anaerobic bacteria. Mo de MIC, MIC50, MIC90 values and percentage of strains resistant indica ted comparable activity for most of the beta-lactams. Geometric and ar ithmetic MICs suggested ceftizoxime to be the most active beta-lactam. statistical analysis of all log(2) values showed that metronidazole w as the most active followed by clindamycin and that ceftizoxime was si gnificantly more active than cefotaxime, piperacillin, ceftriaxone or cefoxitin.