48 Mitrofanoff principles (MTR) were performed on 46 patients (male: female
ratio, 30:16) with a mean age of 9.1 years (range 2.5 to 24 years). The pr
imary diagnoses were neurogenic bladder in 11, infravesical obstruction in
7 and bladder exstrophy-epispadias complex in 28 patients. The most common
type of conduit was appendix (38 cases); other conduits were constructed fr
om the ileum (seven) and lleocaecum (one). In two cases with bladder substi
tution the uterine tube and tubularised bladder stump were used as perineal
MTR. 33 of the 46 children underwent augmentation cystoplasty in conjuncti
on with the MTR procedure. The Malone procedure for antegrade colonic enema
(ACE) was performed at the same stage with MTR in eight cases. To achieve
continence, bladder neck reconstruction was performed in 32 patients and th
e bladder neck was closed in four patients during the same operation and MT
R procedure. The mean follow-up period was 28.7 months (range one month to
57 months). To assess the psychological aspects of the MTR procedure, the R
osenberg Self-Esteem Scales were completed by 12 children older than eight
years of age. Nine patients had problems with the MTR (19.5%). Three append
iceal MTR had strictures at the skin level, 2 of which needed minor surgica
l revisions. A mucocele formation at the skin level of an appendix was remo
ved successfully. We did not observe any complaints among the other appendi
ceal conduits. All the tapered ileum conduits were difficult to catheterise
, and 1 of them had a leakage from the stoma. None of the three transversel
y tubularised ileum MTRs had problems with catheterisation or leakage. A st
ricture of the conduit from the uterine tube was observed. 36 of the 42 pat
ients are now continent, giving a ratio of 86%. The results of the Rosenber
g Self-Esteem Scales revealed that there was an increase in the percentage
of patients with high self-esteem, and a decrease in depressive feelings af
ter the MTR procedure. We conclude that the MTR procedure provides excellen
t continence, offers good prospects of a socially acceptable life with incr
eased self-esteem, and the appendix seems to be the ideal organ for contine
nt urinary diversion, with the transverse tubularised ileal tube as a secon
d choice.