New chiral macrocyclic phosphoramidate self-associated by an intermolecular N-H center dot center dot center dot O=Phydrogen bond

New macrocyclic chiral phosphoramidates containing 2,5-diaryl-1,3, 4-oxadia zole and L-alanine methyl ester units were synthesized by a convenient one- pot procedure, X-ray analysis of-one chiral macrocycle shows that the phosp horamidate molecules are self-associated by intermolecular N-H . . .O = P h ydrogen bonds, the layer stacking along the b axis forming channels paralle l to the b axis. (C) 2001 John Wiley & Sons, Inc.